Fig. 4

Identification and quantitative analyses of UMRs and LMRs in four lens samples. A Distributions of median methylation and number of CpGs in un- or low-methylated regions. Solid horizontal line within boxes: median of median per-region methylation scores. Bottom and top box edges: first and third quartiles, respectively. Bottom and top whiskers: data no smaller than 1.5× the interquartile range from the bottom edge and no greater than 1.5 × the interquartile range from the top edge, respectively. Points: outliers exceeding whisker values. B Log2 enrichment of both UMR and LMR regions across genomic features compared to 20 random shuffles of regions