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Table 5 Statistical comparisons that can be made with X and Y chromosome DNAme array data

From: Who’s afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data

Study design

Method

Case vs. control

Sex-stratified (e.g., X chromosome DNAme in XX female case versus unaffected XX female controls)

X-chromosome inactivation

Use average CpG island promoter DNAme to evaluate whether X linked genes escape or are subject to XCI, as demonstrated in [22, 43]

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