Phthalates impact on the epigenetic factors contributed specifically by the father at fertilization

Table 2 Dibutyl-phthalate (DBP) responsive and paternally provided RNA Element (RE)-containing RNAs (RE-RNAs)

Five fold Paternally enriched				Two fold Paternally enriched
H₁B vs B₁H	H₁B vs HB₂	BH₂ vs B₁H	BH₂ vs HB₂	H₁B vs B₁H	H₁B vs HB₂	BH₂ vs B₁H	BH₂ vs HB₂
ACSM3	STK39	ANKRD36B	VTI1B	ATXN7	ATXN7	EYA3	PKM
ANKRD36C	ERC1	ANKRD36C	AKT3	SMARCC1	PHC3
CAMTA2	PSME4	CTNS	ANKRD36B		SMARCC1
CCDC7	STRN3	CUL2	ERC1
CTNS		KIAA0586	KIFAP3
CUL2		MORC2	NUP98
LMBR1L		NPIPA8	PARP6
MORC2		NUP214	PER1
NUP214		PER1	PHF10
PSME4		PHF10	PSME4
SEC31A		POLDIP2	RGPD6
STK39		PSME4	SLC22A23
STRN3		RGPD6	STK39
		RGPD8
		STK39
		ULK4

RE-RNAs in bold indicate pattern in the same direction upon addition and subtraction of DBP. Paternally provided; five fold paternally enriched or two fold paternally enriched, H₁B; high-DBP (baseline visit) to background DBP (crossover visit), BH₂ background DBP (crossover visit) to high-DBP (crossback visit), B₁H; background DBP (baseline visit) to high-DBP (crossover visit), HB₂ high-DBP (crossover visit) to background DBP (crossback visit). Bold text indicates the RE-RNA is shared within both drug study arms.

ISSN: 1756-8935