Skip to main content
Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Efficient generation of epigenetic disease model mice by epigenome editing using the piggyBac transposon system

Fig. 5

Transgene copy number and DNA methylation levels of TG mice generated by PB and conventional methods. a Transgene copy number in TG mouse embryos (18.5 dpc) generated using the PB system is lower than that produced using a conventional approach. b No significant differences were observed between H19-DMR and promoter region methylation in TG mouse embryos generated by PB and conventional methods. The CpG methylation data of TG mice generated by conventional methods were adopted from our previous report [22]. Error bars, mean ± s.d. *P < 0.05, n.s., not significant (two-tailed Student’s t test)

Back to article page

Epigenetics & Chromatin

ISSN: 1756-8935