Fig. 6From: Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid modelSchematic representation of direct and indirect targets of NaBut treatment on spheroids. A NaBut treatment induces direct effects, such as histone hyperacetylation and indirect, such as chromatin decondensation and transcription activation. B Removal of treatment and reestablishment of standard culture condition revert the NaBut effects and cells return their normal physiologyBack to article page