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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid model

Fig. 6

Schematic representation of direct and indirect targets of NaBut treatment on spheroids. A NaBut treatment induces direct effects, such as histone hyperacetylation and indirect, such as chromatin decondensation and transcription activation. B Removal of treatment and reestablishment of standard culture condition revert the NaBut effects and cells return their normal physiology

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