Fig. 5

A visualisation of the BACH2 region of filtered T1D SNPs on chr6: 89774131–90774131. Tracks displayed below the chromosome 6 ideogram display workflow datasets [3DFAACTS-SNP filtered SNPs, FOXP3-binding sites, Treg ATAC-seq peaks, statistically significant Hi-C interactions in Tregs (5 kb resolution), promoters and enhancers along with cell type-specific data including UCSC Gene Transcript information, T cell subsets (Thelper1 and Treg) expression data, super-enhancer data, 15-state ChromHMM track of T cell lineages. A heatmap showing the Tregs Hi-C interaction matrix (20 kb resolution) is shown below the tracks. The plotted region of the tracks (chr6: 89774131–90774131) are indicated by the green area in the heatmap. The red triangles indicate the topologically associated domains (TADs) called from the Hi-C data