Fig. 3

Visualisation of the CCR3/2/5 region of filtered T1D SNPs on chr3: 45859541–46859541. Tracks displayed below the chromosome 3 ideogram display workflow datasets (3DFACCTS-SNP filtered SNPs, FOXP3-binding sites, Treg ATAC-seq peaks, statistically significant Hi-C interactions of Tregs (5 kb resolution), promoter and enhancer) annotation along with cell type-specific data including UCSC Gene Transcript information, T cell subsets (Thelper1 and Treg) expression data, super-enhancer data, 15-state ChromHMM track of T cell lineages. A heatmap showing the Tregs Hi-C interaction matrix (20 kb resolution) is shown below the tracks. The plotted region of the tracks (chr3: 45859541–46859541) are indicated by the green area in the heatmap. The red triangles indicate the topologically associated domains (TADs) called from the Hi-C interaction data