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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Functions of HP1 proteins in transcriptional regulation

Fig. 2

Simplified phylogeny of the HP1 family in eukaryotes. The HP1 family is highly conserved, but many genomes contain multiple orthologs. In fungi (orange), two HP1 orthologs have evolved over time with divergence in function: Swi6 and Chp2 (shown here for Schizosaccharomyces pombe and S. japonicus as well as the outgroup Neurospora crassa). In plant genomes (green) LHP1 orthologs evolve monophyletically (shown here are genes from Arabidopsis thaliana, Oryza sativa, Carica papaya, and Malus domestica). In invertebrates, the D. melanogaster genome has five orthologs which are conserved to varying degrees across Diptera. One of these genes, HP1b, is most closely related to both HP1 orthologs in other invertebrates (such as hymenopteran insects like Apis mellifera shown here) as well as vertebrate HP1 orthologs from Homo sapiens and Oreochromis niloticus (blue). This phylogenetic tree has been compiled based on information in available in the literature; branch lengths are arbitrary

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