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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci

Fig. 1

Genome-wide analysis of active chromatin in T. cruzi. (A) Overlay of the number of reads per genomic content (RPGC) in FAIRE-seq data for epimastigotes (red line) and its control (blue) on contigs PRFA01000011 and PRFA01000027. Track with the ratio FAIRE/control is depicted in the log2 ratio. Polycistrons are shown in blue tracks; arrows indicate the transcription direction; genes from the conserved compartment, disruptive compartment and both genome compartments are shown in green, red, and orange tracks, respectively. B RPGC log2 ratio of normalized epimastigote FAIRE reads in different T. cruzi compartments. C Active chromatin landscape in core genes (nonmultigenic family) and virulence factors 1 kb upstream and downstream of their respective start (ATG) and end (STOP codon) coding regions. (*** Wilcoxon–Mann–Whitney test with p-value = 0.001)

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Epigenetics & Chromatin

ISSN: 1756-8935