Fig. 5

Regulatory element feature of the region overlapped by the two differentially methylated cytosines (DMC89 and DMC90) and region (DMR40) which were correlated with EBF3 expression. DMCs and DMRs region (represented by the vertical blue line) overlapped a CpG island (CpG1144, represented by the green solid horizontal bar). The DMCs and the DMR overlap a region enriched with histone marks and ATAC peaks, which characterizes the region as strongly active promotors/transcripts in muscle and bivalent/poised TSS in adipose in two male Bos taurus [23]. The EBF3 gene is represented by the dark red line (introns) and dark red blocks (exons). Pink tracks represent the ATAC peaks. The peaks of histone marks H3K27ac, H3K27me, H3K4me1 and H3K4me3 are represented by the red, black, yellow, and green tracks, respectively. The image was obtained from UCSC Genome Browser and edited by the authors