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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation

Fig. 2

Docking model showing the crystal structure of human TET2 with predicted ATP binding sites. ATP docking (SwissDock) was performed to predict potential adenine binding sites on the surface of the protein. Grey—surface representation of TET2 protein (the DNA binding groove is on the opposite side of the protein); purple dots represent predicted top-scoring ATP binding sites; yellow colour denotes sequence motif observed in PAR-binding proteins [26]

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