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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Evolutionary adaptation of the Polycomb repressive complex 2

Fig. 4

Gene and domain structures of PALI1 and PALI2. A PALI1 and PALI2 are splicing variants from the LCOR and LCORL genes, respectively, with C-terminally located PRC2 interacting regions. B Both PALI1 and PALI2 interact with CTBP proteins via a homologous N-terminal domain. While PALI1 also interacts with the G9A complex and possesses an N-terminal nuclear receptor (NR) binding motif, PALI2 has three AT hooks, putatively interacting with DNA

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