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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome

Fig. 3

Refinement of sperm H3K9me2 at gene promoters driving spermatogenesis and distal intergenic regions constrained within Lamina-Associated Domains during epididymal maturation. A Correlation analysis between H3K9me2 ChIP-seq signals derived from sperm isolated from the caput and cauda regions of the epididymis (n = 2). Venn diagrams comparing changes in B broad and C narrow peaks between caput and cauda-derived sperm. D Integrative Genome Viewer tracks of chromosomal regions exhibiting differential H3K9me2 enrichment between caput and cauda-derived sperm. Bar chart representation of the distribution of H3K9me2 across key genomic features between E caput and F cauda-derived samples. Heatmaps displaying the enrichment of H3K9me2 signals across G CpG islands, H regions exhibiting a signature of distal enhancers, or I Lamina-Associated Domains

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Epigenetics & Chromatin

ISSN: 1756-8935