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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Changes in chromatin accessibility landscape and histone H3 core acetylation during valproic acid-induced differentiation of embryonic stem cells

Fig. 5

Cut&Run locus specific and GO Terms. A Heatmaps were generated using the midpoint of the signal block obtained from SEACR analysis. Deeptools were used for heatmap visualization. B Comparative analysis of loci with gained accessibility relative to genebodies and promoter regions in control (Cntl) and VPA-treated (VPA) samples. C Top 15 over-represented GO Terms in biological processes (−log p-value). IGV browser views of differential H3K56ac enrichment at the Pax6 (D) and the Asf1a locus (E) in response to VPA treatment. Coherent broad domains of enrichment were identified by SEACR analysis and are denoted as black bars

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Epigenetics & Chromatin

ISSN: 1756-8935