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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: One-pot universal NicE-seq: all enzymatic downstream processing of 4% formaldehyde crosslinked cells for chromatin accessibility genomics

Fig. 4

Comparison of accessible chromatin features using 25 cells from four different cell lines. A Comparison of FRiP scores of one-pot UniNicE-seq 25 cells in HCT116, HeLa, HEK293 and GM12878. B Correlation analysis of accessible chromatin regions in HCT116, HeLa, HEK293 and GM12878 using one-pot UniNicE-seq. C Upset plot showing common and unique accessible region peaks between HCT116, HeLa, HEK293 and GM12878 using one-pot UniNicE-seq. D Representative IGV screenshot of the normalized read density of the one-pot UniNicE-seq in HCT116, HeLa, HEK293 and GM12878 (scales remain same). E Heatmap showing signal intensity profile of TSS (that includes ± 2 Kb of flanking region) in HCT116, HeLa, HEK293 and GM12878 using one-pot UniNicE-seq. F Peak annotation of one-pot UniNicE-seq in HCT116, HeLa, HEK293 and GM12878. G Genome-wide signal intensity profile plot showing the enrichment of H3K27Ac, H3K4me3, H3K4me1, H3K36me3, H3K9me3 and CTCF in one-pot UniNicE-seq of HCT116, HeLa, HEK293 and GM12878. Peak-start and peak-end are noted as PS and PE

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