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Fig. 8 | Epigenetics & Chromatin

Fig. 8

From: The solid and liquid states of chromatin

Fig. 8

reproduced with modifications from [220].

Hierarchical chromatin organization in the nucleus—a simplified view. The negatively charged 10-nm fiber is compacted into chromatin domains (e.g., topologically associating domain [TAD]/contact domain/loop domain) [136,137,138,139]. The domains are clustered over long distances to form chromatin compartments [147]. Compartments generally represent a transcriptionally active chromatin state (compartment A) and an inactive chromatin state (compartment B). A single interphase chromosome is occupied in a chromosome territory (highlighted as different colors) [219]. This illustration was

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