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Table 9 Summary of the number of CpG sites by their genomic location and methylation level

From: Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

Genome feature 0–25% Methylation 25–50% Methylation 50–75% Methylation 75–100% Methylation Total CpGs
Intergenic region 589,261 (4.6%) 1,149,789 (8.9%) 3,112,308 (24.2%) 7,988,953 (62.2%) 12,840,311
Gene body 132,403 (3.9%) 212,133 (6.2%) 607,207 (17.7%) 2,474,678 (72.2%) 3,426,421
Promoter 13,500 (19.8%) 5950 (8.7%) 12,777 (18.7%) 35,941 (52.7%) 68,168
First exon 5000 (12.4%) 2755 (6.8%) 7914 (19.7%) 24,557 (61.0%) 40,226
Remaining exons 5649 (2.3%) 10,047 (4.1%) 35,845 (14.8%) 190,754 (78.7%) 242,295
Introns 122,441 (3.9%) 199,976 (6.3%) 566,193 (17.9%) 2,267,569 (71.8%) 3,156,179
  1. Sites are binned into four levels of methylation: 0–25%, 25–50%, 50–75%, and 75–100%