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Table 9 Summary of the number of CpG sites by their genomic location and methylation level

From: Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

Genome feature

0–25% Methylation

25–50% Methylation

50–75% Methylation

75–100% Methylation

Total CpGs

Intergenic region

589,261 (4.6%)

1,149,789 (8.9%)

3,112,308 (24.2%)

7,988,953 (62.2%)

12,840,311

Gene body

132,403 (3.9%)

212,133 (6.2%)

607,207 (17.7%)

2,474,678 (72.2%)

3,426,421

Promoter

13,500 (19.8%)

5950 (8.7%)

12,777 (18.7%)

35,941 (52.7%)

68,168

First exon

5000 (12.4%)

2755 (6.8%)

7914 (19.7%)

24,557 (61.0%)

40,226

Remaining exons

5649 (2.3%)

10,047 (4.1%)

35,845 (14.8%)

190,754 (78.7%)

242,295

Introns

122,441 (3.9%)

199,976 (6.3%)

566,193 (17.9%)

2,267,569 (71.8%)

3,156,179

  1. Sites are binned into four levels of methylation: 0–25%, 25–50%, 50–75%, and 75–100%