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Fig. 7 | Epigenetics & Chromatin

Fig. 7

From: Histone deacetylase inhibition leads to regulatory histone mark alterations and impairs meiosis in oocytes

Fig. 7

Increased proliferation in PB-exposed PND5 ovaries. A Paraffin sections of PND5 ovaries were immunostained for MSY2 (red) in the control (top) and PB (bottom) groups. B The follicles were scored for 5 biological replicates. The scores were averaged and plotted and are presented as the number of follicles per section ± SEM; *p < 0.05, nonparametric Mann–Whitney test. C Representative image of paraffin sections of PND5 ovaries immunostained for PCNA (green) or phosphorylated histone 3 at serine 10 (red) in the control (top) and PB (bottom) groups. Since PCNA and phosphorylated -histone H3 at serine 10 showed heterogeneity in cell type staining, quantitative analysis of fluorescence-positive cells was not performed

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