Skip to main content

Table 1 The percentage of variably escaping (VE) genes found by DNAme that have significant differences in epigenetic marks (BH corrected p value < 0.01)

From: Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation

VEtype n VE transcripts n VE genes H3K4me1 H3K4me3 H3K9me3 H3K27ac H3K27me3 H3K36me3 expression
Across datasets 22 17 6% 17% 18% 17% 17% 16% 0%
Across tissues 70 40 12% 28% 7% 16% 14% 21% 39%
Between TSSs 2 1 0% 100% 0% 0% 100% 0% 0%
Within blood 74 51 2% 8% 2% 12% 4% 8% 3%
Within brain 10 9 13% 0% 0% 13% 0% 11% 0%
Within breast 29 24 0% 0% 4% 0% 0% 4% 0%
Within colon 8 4 25% 25% 0% 0% 0% 20% 0%
Within thyroid 45 27 16% 0 7% 10% 0% 24% 0%
  1. Different categories of variable escape are included on the left. The number of variably escaping (VE) transcripts found per category and the number of unique genes are also included. Categories with 25% or more variably escaping genes found significant are bolded, excluding variable escape between TSSs for which only 1 gene was available