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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription

Fig. 2

Analysis of candidate gene expression in the cerebellum and heart. Examination of candidate genes within the Oxidative Phosphorylation, Mitochondrial Dysfunction, and EIF2 Signaling pathways using RNA samples derived from morphologically normal A cerebellum and B heart. Tissues were isolated from control, alcohol-exposed but phenotypically normal offspring, and alcohol-exposed affected offspring, exhibiting ocular and cortical patterning defects. Analysis of gene expression conducted using RT-qPCR, normalized to transcripts encoding H2Afz and Ywhaz. (n = 8 Control, 9 Unaffected, 7 Affected). Error bars represent the SEM, *P < 0.05, **P < 0.01, ***P < 0.001

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Epigenetics & Chromatin

ISSN: 1756-8935