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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Three putative DNA methyltransferases of Verticillium dahliae differentially contribute to DNA methylation that is dispensable for growth, development and virulence

Fig. 4

Genes and TEs that are induced in the Verticillium dahliae Hp1 and Dim5 mutants do not associate with H3K9me3-marked chromatin. Differentially expressed genes (a) and TEs (b) in the mutants relative to wild-type. Induced genes and TEs are indicated in blue, repressed genes and TEs in red. The number of genes and TEs that are induced and repressed in both the Hp1 and Dim5 mutants are indicated by opaque coloring in black rectangles. c Gene Ontology (GO) terms that are enriched (fold change > 1, p.adj < 0.01) in the set of genes that are induced in both the Hp1 and Dim5 mutant. (d). Whole-chromosome plot displaying the location of induced genes (in blue) and TEs (in red) on chromosome 5 as an example. Clusters of induced genes and TEs are indicated as blue and red rectangles, respectively. H3K9me3-ChIP signal along the chromosome is indicated in green in the upper track. adaptive genomic regions [23] are highlighted in yellow. The minimal distance of genes and TEs to H3K9me3-enriched genomic regions (e) and to adaptive genomic regions (f). Asterisks indicate statistical differences (Wilcoxon signed rank test, p < 0.01) between genes and TEs induced in both the ∆Hp1 and ∆Dim5 mutants and those that are not induced in the mutants

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