Species | KMT1 mutant | KMT6 mutant | HP1 mutant | References |
---|---|---|---|---|
Podospora anserina | ||||
Growth and development | Reduced production of aerial hyphae Slight growth defect Delay in resuming vegetative growth | Very poor growth Less pigmentation Overproduction of conidia Misshapped fructification Defect in spore germination | Reduced production of aerial hyphae Slight growth defect | This study |
Chromatin and regulation ChIP-seq | Loss of H3K9me3 | Loss of H3K27me3 and H3K9me3 | Broader H3K9me3 domains | |
Neurospora crassa | ||||
Growth and development | Reduced growth Affected in sexual development | None | Reduced growth Affected in sexual development | Basenko et al. [34]; Freitag et al. [48]; Jamieson et al. [33, 35]; Klocko et al. [36] |
Chromatin and regulation ChIP-seq and Hi-C | Affected in DNA methylation Relocalization of H3K27me3 Loss of H3K9me3 H3K27me3 relocation and diminution | Loss of H3K27me2/3 Altered in chromosome conformation | Affected in DNA methylation relocation of H3K27me2/3, superimposition with H3K9me3 | |
Fusarium verticilloides | ||||
Growth and development | Defects in conidiation, perithecium production and fungal virulence Overpigmentation | N/A | N/A | Gu et al. [82] |
Chromatin and regulation | N/A | N/A | N/A | |
Fusarium graminearum | ||||
Growth and development | N/A | Growth defects Sterility Overpigmentation Reduced virulence | Overpigmentation | |
Chromatin and regulation ChIP-seq | N/A | Loss of H3K27me3 Constitutive expression of genes encoding mycotoxins pigments-producing enzymes and other SM | Enhanced activity of activity of biosynthetic cluster genes | |
Epichloë festucae | ||||
Growth and development | Reduced vegetative growth Deregulation of symbiosis | Deregulation of symbiosis | Deregulation of symbiosis | |
Chromatin and regulation ChIP-qPCR | Derepression of symbiosis-specific alkaloid genes clusters | Derepression of symbiosis-specific alkaloid genes clusters | Derepression of symbiosis-specific alkaloid genes clusters | |
Magnaporthe oryzae | ||||
Growth and development | Reduced vegetative growth Reduced virulence | Reduced vegetative growth Severe reduction in conidiation Slight defects in appressorium formation Reduction in pathogenicity | N/A | Pham et al. [46] |
Chromatin and regulation WB | Loss of H3K9me3 | Loss of H3K27me3 | N/A | |
Zymoseptoria tritici | ||||
Growth and development | Reduced vegetative growth Reduced virulence | Reduced virulence | N/A | Möller et al. [45] |
Chromatin and regulation ChIP-seq | Loss of H3K9me3 TE activation and genomic rearrangements H3K27me3 relocation Reduction of H3K27me3 | Loss of H3K27me3 Increased stability of accessory chromosomes | N/A | |
Aspergillus nidulans | ||||
Growth and development | No developmental phenotype | N/A | No developmental phenotype | Reyes-Dominguez et al. [85] |
Chromatin and regulation | Enhanced expression of a subset of secondary metabolite (SM) clusters | N/A | Enhanced expression of a subset of secondary metabolite (SM) clusters | |
Aspergillus fumigatus | ||||
Growth and development | Reduced vegetative growth delayed conidiation | N/A | Reduced vegetative growth and delayed conidiation | Palmer et al. [86] |
Chromatin and regulation | N/A | N/A | N/A | |
Leptosphaeria maculans | ||||
Growth and development | Reduced vegetative growth Reduced virulence | N/A | Reduced vegetative growth | Soyer et al. [87] |
Chromatin and regulation ChIP-seq (WT only) | Up-regulation of pathogenicity-related genes | N/A | Up-regulation of pathogenicity-related genes | |
Penicillium oxalicum | ||||
Growth and development | N/A | N/A | Reduced vegetative growth Delayed conidiation | Zhang et al. [88] |
Chromatin and regulation | N/A | N/A | N/A |