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Table 1 Early-life undernutrition induced nascent transcription alteration of metabolic enzymes

From: Early-life undernutrition induces enhancer RNA remodeling in mice liver

Metabolic enzymes

Cyp3a11

Cytochrome P450 3A11

Cyp2c40

Cytochrome P450 2C40

Cyp3a25

Cytochrome P450 3A25

Cyp4a12a

Cytochrome P450 4A12A

Cyp2b10

Cytochrome P450 2B10

Sik1

Salt Inducible Kinase 1

Nudt7

Nudix Hydrolase 7

Ugt2b35

UDP-glucuronosyltransferase

Bhmt

Betaine--Homocysteine S-Methyltransferase

B3galt1

Beta-1,3-Galactosyltransferase 1

Acsl1

Acyl-CoA Synthetase Long Chain Family Member 1

Ces1d

Carboxylesterase 1D

  1. Significantly changed genes related to metabolic pathways were selected to compare their expression between GRO-seq and RNA-seq, both showed high consistency between eRNA, genebody and RNA-seq expression at the same ages PRD mice