Genome-wide impact of hydrogen peroxide on maintenance DNA methylation in replicating cells

Table 1 The top 20 most significant differentially methylated genes with a log₂FC > 1.2 at the 4-h time point, ordered by magnitude of log₂-fold change

Probe ID	log₂FC (4 h)	Adj p-val (4 h)	log₂FC (72 h)	Chromosome	Location	Gene
cg21150892	2.94	0.04	0.27	1	183,846,009	RGL1
cg26890348	2.48	0.03	0.87	13	52,637,074
cg24024260	− 2.29	0.01	− 0.40	2	182,174,340	LOC101927156
cg05047191	− 2.23	0.04	− 0.33	12	15,304,108	RERG
cg00192946	− 2.19	0.01	− 0.95	X	32,430,274	DMD
cg21426441	− 2.19	0.04	− 0.77	X	17,260,259
cg14954143	− 2.13	0.02	− 0.79	3	162,071,211
cg02187176	2.1	0.04	0.61	13	96,367,153	DNAJC3
cg23727674	− 2.09	0.03	− 0.30	2	148,602,993	ACVR2A
cg25969765	− 2.07	0.03	− 0.80	18	58,350,853
cg11372135	− 2.05	0.01	− 0.54	10	18,629,284	CACNB2
ch.X.16400295F	− 2.04	0.02	− 0.76	X	16,490,374
cg03012782	− 1.87	0.03	− 1.08	3	112,250,543
cg06780892	− 1.87	0.04	− 0.77	7	20,638,177
cg15074165	− 1.85	0.03	− 1.00	X	71,792,745	HDAC8
cg09333215	− 1.84	0.01	− 0.17	1	88,475,866
cg01492091	− 1.81	0.02	− 0.91	7	31,460,998
cg08892255	− 1.8	0.03	− 1.02	20	21,928,217
cg07042371	− 1.77	0.02	− 0.71	5	54,468,233	MIR449C
cg01769501	− 1.77	0.04	− 0.67	4	76,912,251	SDAD1

ISSN: 1756-8935