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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature

Fig. 5

Consensus DMR profiles for DNMT3L overexpression across all phases of neural differentiation. a Euler diagram of gene symbol overlaps for the genotype comparison at each phase of neural differentiation. b Heatmap of hierarchal clustering of Z-scores for the consensus DMRs that are derived from merging the DMRs from each phase comparison by sequence overlap. c Bar plot of comparison specific p-values from the meta-analysis of the least dispensable significant slimmed GO enrichments (pmeta < 0.05)

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Epigenetics & Chromatin

ISSN: 1756-8935