Fig. 3From: Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signatureDifferentially methylated region (DMR) profiles and slimmed gene ontology (GO) enrichments for DNMT3L overexpression at the different phases of neural differentiation. The heatmaps represent hierarchal clustering of Z-scores, which represent the number of standard deviations from the mean of the non-adjusted individual smoothed methylation value for each DMR. The bar plots represent the least dispensable significant enrichments (p < 0.05)Back to article page