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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature

Fig. 3

Differentially methylated region (DMR) profiles and slimmed gene ontology (GO) enrichments for DNMT3L overexpression at the different phases of neural differentiation. The heatmaps represent hierarchal clustering of Z-scores, which represent the number of standard deviations from the mean of the non-adjusted individual smoothed methylation value for each DMR. The bar plots represent the least dispensable significant enrichments (p < 0.05)

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