Histone crotonylation | Target | Regulatory role | References |
---|---|---|---|
Histone Kcr | PGC-1α and sirtuin-3 | Promoting transcription | [11] |
Ptk2, Tshz3, Wapal | Promoting transcription | [19] | |
H2BK12Cr | Pin4, Ccdc160, Tceal, Rnf138rt1, and 4933436I01Rik | Promoting transcription | [10] |
H3K4Cr | HIV LTR | Promoting transcription | [35] |
H3K9Cr | Pro-growth genes | Inhibiting transcription | [9] |
H3K18Cr | Il6, Gbp2, Ifit1, and Rsad2 | Promoting transcription | [15] |
RANDP3L, AOX1, GRPR, and NCAM1 | Promoting transcription | [20] | |
HIV long-terminal repeat (LTR) | Promoting transcription | [35] | |
H3K27Cr | Endocytosis-related genes | Inhibiting transcription | [8] |