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Table 1 DNA methylation in ocular disease

From: Epigenetic regulation of retinal development

Disease Gene DNA modification References
Age-related macular degeneration (AMD) SKI, GTF2H4, TNXB
GSTM1/5
IL17RC
Hypermethylation
Hypomethylation
[161,162,163,164]
Cataract Klotho, Cryaa, GSTP1, TXNRD2 Hypermethylation [165,166,167,168]
Glaucoma
*Open-angle glaucoma
Alu, Hsp70
*HERV-K
Hypomethylation
Hypermethylation
[169, 170]