Table 1 DNA methylation in ocular disease
| Disease | Gene | DNA modification | References |
|---|---|---|---|
| Age-related macular degeneration (AMD) |
SKI, GTF2H4, TNXB GSTM1/5 IL17RC |
Hypermethylation Hypomethylation | [161,162,163,164] |
| Cataract | Klotho, Cryaa, GSTP1, TXNRD2 | Hypermethylation | [165,166,167,168] |
|
Glaucoma *Open-angle glaucoma |
Alu, Hsp70 *HERV-K |
Hypomethylation Hypermethylation | [169, 170] |