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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: DNA methylation differs extensively between strains of the same geographical origin and changes with age in Daphnia magna

Fig. 2

Methylation status correlates with Strain. a PCA plot of replicates for principal components one and two for the top 10,000 most variably methylated CpGs by beta value; C32 = yellow, KA53 = blue. b Hierarchical clustering of replicates with colouring as for a), replicates split by strain with 100% approximately unbiased p-value (red) and bootstrap probabilities (black). c CpGs with greater than 5% methylation combined across replicates are enriched in the coding regions of exons versus the rest of gene bodies. d CpGs with greater than 5% methylation combined across replicates are concentrated in exons two to five in line with previous studies investigating DNA methylation in D. magna [8]

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Epigenetics & Chromatin

ISSN: 1756-8935