Fig. 5

Differential chromatin accessibility within enhancer regions. Significant differential peaks annotated as intergenic were compared against tissue-specific enhancers. a All enhancer regions across each of the four times. b Super-enhancer regulated genes. Red and blue shading indicate fold-changes, while grey indicates that no significant peaks were associated with that enhancer at that time. Some enhancer regions contain more than one peak, explaining why there are multiple fold-changes at some times. c Gene Ontology enrichment from the large number of enhancer-associated genes at 48 h. BP and MF correspond to biological process and molecular function