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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences

Fig. 6

Intergenic, colocalised Pf H2A.Z, H3K18ac and H3K27ac mark well-positioned nucleosomes within a region of exposed DNA. a ChIP, b % GC, gDNA normalised ATACseq [41], MNaseSeq readcounts [43] and (c) ChIPseq, matched, stranded RNASeq rpkm and ATACseq plotted across the 2645 colocalised Pf H2A.Z, H3K18ac and H3K27ac schizont-stage intergenic peaks. The plot profiles and heatmaps are centred on the Pf H2A.Z peak summits. The heatmap was sorted in descending order of the schizont-stage RNAseq rpkm of the closest downstream gene

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Epigenetics & Chromatin

ISSN: 1756-8935