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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Characterization of universal features of partially methylated domains across tissues and species

Fig. 1

Comparison of PMD identification methods. a Comparison of PMD estimates from all three methods on chromosome 6 for three samples with substantial variation in PMD depth. b Pairwise Jaccard index distributions comparing within-cancer-type and between-cancer-type for PMD sets identified using each method. c Pairwise Jaccard index heatmaps of TCGA cancer sample PMDs identified by each method. d Effect of downsampling and low coverage on PMD estimates. e Jaccard index of downsampled PMD estimates with their respective full-coverage sample for all human PMD-containing samples

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