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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Histone N-alpha terminal modifications: genome regulation at the tip of the tail

Fig. 4

Putative N-terminal acetylation of H1 histone variants. The N-alpha terminus of initiator methionine (iMet) at H1.1-1.6, H1.0 and H1.10 variants can be acetylated by NatE. Upon excision of iMet, NatA can acetylate the N-terminal tip of serine 1 (S1), alanine 1 (A1) or threonine 1 (T1) at H1.1-1.6, H1.0 and H1.10 variants, respectively. Histone H1.9 with N-terminal sequence of iMet-Leucine 1 (L1) can be targeted by NatC or NatE while the N-terminal iMet-Glutamine 1 (Q1) 1 sequence of H1.7 can be acetylated by NatB [21]

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