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Table 1 Histone mutations tested during sporulation

From: Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark

 

Number of mutations

Testeda

Sporulation defectsb

This study (s288c)

 H2A

52

36 (69%)

 H2B

66

42 (64%)

This study (SK1)

 H2A

55

28 (51%)

 H2B

69

47 (68%)

Govin et al. 2010 (SK1)

 H3

54

13 (24%)

 H4

34

15 (44%)

Total (SK1)

212

103 (48%)

  1. aExcluding lethal mutations
  2. bWith sporulation efficiency below 40% and 80% for s288c and SK1 genetic backgrounds, respectively. Expressed as a percentage of the total of mutant tested by category (rows)
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Epigenetics & Chromatin

ISSN: 1756-8935