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Fig. 9 | Epigenetics & Chromatin

Fig. 9

From: Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark

Fig. 9

Mouse H2BK34me2 is detected in meiosis during spermatogenesis. a Alignment of H2B sequences in yeast and human around the yeast H2BK37 residue. Sc, Saccharomyces cerevisiae. Mm, Mus musculus. b H2BK34me2 levels during spermatogenesis. Cells were purified at different stages and analyzed by western blot. M, meiosis (spermatocytes); R, round spermatids; E, elongating spermatids. C. H2BK34me2 detection in mouse seminiferous tubules analyzed by immunofluorescence. H2BK34me2 were co-detected with Sycp2, a classic marker of meiosis. Insets are magnified in the bottom images

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