Fig. 1
From: HiCoP, a simple and robust method for detecting interactions of regulatory regions
CoP assay enriches regulatory regions. a Schematic diagram of CoP assay. b, c CoP- and FAIRE-qPCR detected the enrichment of regulatory regions in human leukemia cell line K562 cells and mouse thymocytes. GAPDH pro, GAPDH gene promoter; GAPDH 5.5 kb, 5.5 kb upstream of GAPDH promoter; CCND1 CBE, a CTCF binding site in CCND1 locus; CCND1 CBE 27 kb, 27 kb upstream of the CCND1 CBE; MageA2, MageA2 gene promoter; B2m, B2m gene promoter; Tcra Ea, Tcra gene enhancer Eα; Tcra Ea 50 kb, 50 kb downstream of the enhancer Eα; Dad1 CBE, a CTCF binding site in Dad1 gene. The data are plotted as mean ± SD of two independent experiments