Fig. 1

Highly conserved YEATS domain is non-essential for viability in yeast. a Schematic of wt and mutant Taf14 proteins used in this study. Wt Taf14 protein contains a highly conserved YEATS domain in its N-terminus. Mutant Taf14 protein without the YEATS domain (Taf14_ΔYEATS) lacks amino acids 6–121 and mutant Taf14 protein with a non-functional YEATS domain (taf14_W81A) has substitution of Trp81 to alanine. b Tenfold serial dilutions of cells with single or double-knockout of TAF14, YAF9 and SAS5 were spotted onto SC plates and grown at 30 °C for 2 days. c Tenfold serial dilutions of taf14_ΔYEATS or taf14_W81A cells combined with YAF9 and SAS5 deletions. Cells were spotted onto SC plates and grown at 30 °C for 2 days