Epigenetics & Chromatin

Table 1 DMRs overlapping DAMEs

From: DAMEfinder: a method to detect differential allele-specific methylation

	DMR state	Total DMRs	DMRs with DAMEs	DAMEs with DMRs	Gain/loss ASM
CIMP	Hyper	5040	2171	2789	2694/95
CIMP	Hypo	1713	114	116	88/28
Non-CIMP	Hyper	3187	76	77	61/16
Non-CIMP	Hypo	10,033	88	88	64/24

Hyper- or hypo-methylated DMR refers to the increase or decrease of methylation in cancers in comparison with paired normal samples, while gain or loss of ASM refers to whether cancers have more or less allele specificity than paired normal samples

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ISSN: 1756-8935

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