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Fig. 9 | Epigenetics & Chromatin

Fig. 9

From: Linker histone epitopes are hidden by in situ higher-order chromatin structure

Fig. 9

a, b Average profiles of DNA methylation aligned with respect to the centers of nucleosomes determined in HL-60/S4 cells using MNase-assisted xChIP-seq of histone H3 for nucleosomes inside peaks enriched with xChIP H1.2 (black) and xChIP H1.5 (orange), as well as xxChIP-seq of histone H1.2 (blue) and H1.5 (green). a Only nucleosomes inside H1-enriched peaks inside CpG islands are considered. b Only nucleosomes inside H1-enriched peaks outside CpG islands. c Average profiles of H1 epitope exposure around individual CpGs genome-wide. d Average profiles of DNA methylation around centers of H1-enriched peaks

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