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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: EPIGENE: genome-wide transcription unit annotation using a multivariate probabilistic model of histone modifications

Fig. 4

Performance of EPIGENE compared to existing RNA-seq-based transcription unit prediction methods: Cufflinks and StringTie. a Set of gold standard regions obtained by combining RNA Polymerase II ChIP-seq and Nascent RNA-seq profiles. b Contingency matrix used for method comparison. c Receiver-operating characteristic curve. d Precision–recall curve. e Area under ROC and PRC curve for varying RNA Polymerase II resolution for EPIGENE, Cufflinks and StringTie

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