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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices

Fig. 5

Nanochannel stretching of YOYO-1 stained DNA under MeCP2 binding. a Fluorescence images of methylated \(\lambda\)-DNA (left) and methylated DNA with MeCP2 (right). b Fluorescence images of unmethylated \(\lambda\)-DNA (left) and unmethylated DNA with MeCP2 (right). The scale bar represents \({5}\,\upmu \hbox {m}\). c Impact of MeCP2 binding on \(R_g\) for methylated DNA (blue bare DNA N=38, yellow with MeCP2 N=34). d Impact of MeCP2 binding on \(R_g\) for unmethylated DNA (blue bare DNA N=44, yellow with MeCP2 N=33)

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