Fig. 6

Altered CpG methylation at NEFM human DNMT1-dependent locus. a Genomic location of the identified NEFM DNMT1-dependent region. The DNA element and distance from the transcription start site are annotated in black. The transcription factor-binding site for CTCF was annotated from ENCODE v2 and ENCODE Uniform TFBS tracks in Genome Browser. The primer region box indicates the amplified region for Bisulfite-sequencing. b The percent methylation of all CpG sites within the first 200 base-pairs of the amplified region. Delta indicates the change in the mean CpG methylation percentage and the associated false-discovery rate. c The percent methylation of individual CpG sites within the amplified region. Significant differentially methylated cytosines are indicated by * (Δ > 1%; q value < 0.01)