Fig. 4

Localization of linker histone H1t in the mouse rDNA element. a Peak distribution of H1t across various regions of the rDNA element [43]. Distribution of H1t peaks with respect to SINE elements (green dotted lines) localized in the rDNA element. The red lines demarcate various regions of the rDNA element, blue lines are the H1t peaks, and the various regions of the rDNA element have been labeled below the peak distribution maps. Density plot of H1t peaks overlapping with methylated CpGs (SRS557654) in b. rDNA and c extranucleolar genomic regions. The y-axis represents the density function and the x-axis represents the bandwidth parameter. N represents the number of observations. The red lines demarcate various regions of the rDNA element [43], blue lines are the H1t peaks, and the various regions of the rDNA element have been labeled below the peak distribution maps. d Level of DNA methylation in the extranucleolar, nucleolar and the total H1t peaks. The data have been plotted in terms of the number of methylated cytosines as mean ± SD