Fig. 3From: Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent miceDNE does not impact TET2 content in the frontal cortices, striata, or hippocampi. Representative Western blot images and densitometric measurements of TET2 abundance in frontal cortices (nF1Veh = 7, nF1NIC = 8, and nF2NIC = 10), striata (nF1Veh = 7, nF1NIC = 9, and nF2NIC = 9), and hippocampi (nF1Veh = 8, nF1NIC = 9, and nF2NIC = 8). a TET2 abundance in frontal cortices. Frontal cortical TET2 content is unaltered in F1 NIC and F2 NIC mice. b TET2 abundance in striata. Striatal TET2 content is unaltered in F1 NIC and F2 NIC mice. c TET2 abundance in hippocampi. Hippocampal TET2 content is unaltered in F1 NIC and F2 NIC mice. FCX frontal cortices, STR striata, HIPP hippocampi, TET2 ten-eleven translocase methylcytosine dioxygenase 2, TET2 (1) TET2 isoform 1, TET2 (2) TET2 isoform 2, TET2 (3) TET2 isoform 3, TBP TATA-binding protein. All data are mean ± SEMBack to article page