Fig. 5

JMJD1B gene mutations correlate with high cancer incidence and with genomic instability. a The graph shows the incidence of JMJD1B mutations among patients with different types of cancers. Mutations include point mutations and insertion/deletions. Affymetrix data were obtained from the NIH Cancer Data Portal. b The graph shows the total number of mutations found per each cancer type on the JMJD1B gene. The data include point mutations and insertion/deletions. c Genomic instability index, expressed as log10, was calculated from the population of patients that contain mutations (point mutations and insertion/deletion) on the JMJD1B gene. The data are shown for the following cancers: KIRC, OV, ACC, and UCEC, from data derived from healthy tissues (blue) and primary tumor (red) of the same patients. Abbreviations are defined in Additional file 1: Figure S2. d Statistical analyses between the JMJD1B vs. SETD2 mutant populations and sample types (primary tumor vs. normal tissue) in the four cancers of interest