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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Transcription-independent TFIIIC-bound sites cluster near heterochromatin boundaries within lamina-associated domains in C. elegans

Fig. 3

Extra-TFIIIC sites are clustered in autosomal arms. a Distribution of TFIIIC sites across chromosomes. Permutations of TFIIIC sites were performed across the genome. P, empirical P-value based on the 2000 permutations. b Distribution of TFIIIC sites within chromosomes. Horizontal color bars indicate chromosomal domains defined by Rockman and Kruglyak [24]. c Fraction of TFIIIC sites within chromosomal domains. Permutations of TFIIIC sites were performed within chromosomes. P, empirical P-value based on the 2000 permutations. d A representative genomic region harboring clusters of extra-TFIIIC sites. e Red, distribution of the interval size between two adjacent extra-TFIIIC sites. Gray, distribution of the mean of the interval sizes of permutated TFIIIC sites (2000 means representing 2000 permutations). Permutations were performed within chromosomal domains (i.e., center and left/right arms)

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