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Table 1 Variants predicted by applying MethylToSNP to the YRI and CEU HapMap methylation datasets

From: MethylToSNP: identifying SNPs in Illumina DNA methylation array data

Set

SNP predictions in dataset (#)

Overlap with dbSNP 142 (#)

Overlap with dbSNP 146 (#)

Potential novel SNPsa (#)

Total array sites removed by dbSNP 142 filteringb,c (#)

Total array sites removed by dbSNP 146 filteringb,c (#)

Median reliability scores of predicted SNPs

# novel SNPs with reliability scores ≥ 0.5

YRI

37

3

9

28

3563

5677

0.01875

6

CEU

283

37

57

226

3329

5629

0.011

31

  1. Default threshold values used
  2. aAfter filtering for known SNPs
  3. bDirect overlap of C in CpG position
  4. cAfter removing MethylToSNP