Fig. 6

Hmgn2-knockout cells show a reduction in active histone H3 modifications at bivalent and active gene loci. ChIP-PCR assays in control and knockout cell lines for H3K4me3 (a), H3K9ac (b), H3K27ac (c) and H3K27me3 (d). Data show the enrichment of each modification as a percentage of input. Statistical significance between parental and experimental lines was determined using the Student’s T test, with Bonferroni correction for multiple testing (*p < 0.005, .p < 0.001, ^#p < 0.0001). Data for H3K122ac, H3 and H1 are shown in Additional file 1: Figure S11