Fig. 1

Generation of Hmgn1 and Hmgn2 knockout P19 lines. Western blot analysis of a HMGN1 and b HMGN2 protein levels in clonal P19 lines; β-tubulin is shown as a loading control. c Hmgn1 and Hmgn2 mRNA expression as determined by qRT-PCR in control and Hmgn-knockout cells. The graph represents the average fold change relative to parental P19 cells (n = 3–10) (***p < 0.0001)