Fig. 5

Differential expression of HOX genes. a Heatmaps visualizing the gene expression level (logged transcripts per million [TPM]) of four HOX clusters and two long non-coding RNAs, LINC01117 (Hotdog) and LINC01116 (Twin of Hotdog). Blue vertical bars indicate the 5′ HOX genes. b Read distribution around the HOXD cluster (chr2: 176.8–177.6 Mbp). Bottom: topological interaction frequency, telomeric domain (T-DOM) and centromeric domain (C-DOM) identified by Hi-C data for HUVECs. c Comparison of read profiles around the HOXD region for four EC types